Current position

since 2017
Research assistant in the Department of Anatomy in the Department of Human Medicine at the University of Oldenburg

Academic training and scientific career

since 2017
Research Associate in the Department for Human Medicine at the University of Oldenburg

2012 - 2017
Research assistant for the Teaching Coordination of Anatomy at the School of Medicine and Health Sciences at the University of Oldenburg

Dec. 2010
Obtained the qualification as a specialist in anatomy

2001 - 2012
Research assistant at the Institute of Anatomy at the University of Leipzig

2001
Doctorate with the topic: "The changes in oxygen partial pressure in the human tibialis anterior muscle before, during and after tourniquet-induced ischaemia"

Evaluation: magna cum laude

1998 - 2001
Research assistant in the Department of Anatomy and Cell Biology at the University of Ulm

1999
Licence to practise medicine

1997 - 1998
Internship in the Department of General Surgery at the University Hospital Regensburg

1989 - 1996
Medical studies at the University of Ulm and Regensburg

Memberships in scientific societies

• Neuroscience Society
• German Anatomical Society

Maier EC, Ödemis V, Bräuer AU. Digitally based clinical-orientated anatomy: the future of teaching. Die Chirurgie. https://doi.org/10.1007/s00104-024-02211-w. 08 January 2025.

Uslar V-N; Strotmann C; Ödemis V; Tabriz N; Salzmann D; Weyhe DA (2023): Application of augmented reality devices in anatomical teaching depending on spatial imagination in the medical teaching of the liver. In: Zeitschrift für Gastroenterologie Stuttgart [u.a.] : Thieme, 1997 Band 61 (2023), Nummer 8, Seite e609, insgesamt 1 Seite Online-Ressource. Available online at https://www.thieme-connect.de/products/ejournals/conferencepdf/126907/10.1055/s-00000094.pdf.

Use of augmented reality in university clinical anatomy teaching on the pancreas (2022); D Weyhe, C Strotmann, MA Bisotti, S Pelzl, V Ödemis, D Salzmann; Journal of Gastroenterology 60 (08), KA479

Yahya I, Boeing M, Pu Q, Puchert M, Ödemis V, Engele J, Brand-Saberi B, Morosan-Puopolo G. CXCR4 and SDF-1 are critically involved in the formation of facial and non-somitic neck muscles. Scientific reports. 2020 10(1): 1-14.

Masyuk M, Abduelmula A, Morosan-Puopolo G, Ödemis V, Rehimi R, Khalida N, Yusuf F, Engele J, Tamamura H, Theiss C, Brand-Saberi B.: Retrograde migration of pectoral girdle muscle precursors depends on CXCR4/SDF-1 signalling. Histochem Cell Biol. 2014;142(5):473-88

Lipfert J., Ödemis V., Wagner DC., Boltze J., Engele J.: CXCR4 and CXCR7 form a functional receptor unit for SDF-1/CXCL12 in primary rodent microglia. Neuropathol Appl Neurobiol. 2013; 39(6): 667-80

Lipfert J., Ödemis V., Engele J.: Grk2 is an Essential Regulator of CXCR7 Signalling in Astrocytes. Cell Mol Neurobiol 2013; 33(1): 111-8

Hunger C., Ödemis V., Engele J.: Expression and function of the SDF-1 chemokine receptors CXCR4 and CXCR7 during limb muscle development and regeneration. Exp. Cell Res. 2012; 318: 2178-2190

Glisic D., Lehmann C., Figiel F., Ödemis V., Lindner R., Engele J.: A novel cross-talk between endothelin and ErbB receptors controlling glutamate uptake into astrocytes. J Neurochem. 2012; 122(4): 844-55

Ödemis V., Lipfert J., Kraft R., Hajek P., Abraham G., Hattermann K., Mentlein R., Engele J.: The presumed atypical chemokine receptor CXCR7 signals through Gi/o proteins in primary rodent astrocytes and human glioma cells. Glia 2012; 60 (3): 372-381

Ödemis V., Boosmann K., Küry P., Engele J.: CXCR7 is an active component of SDF-1 signalling in astrocytes and Schwann cells. J. Cell. Sci. 2010; 123(Pt 7): 1081-8

Göttle P., Kremer D., Jander S., Ödemis V., Engele J., Hartung HP, Küry P.: Activation of CXCR7 receptor promotes oligodendroglial cell maturation. Ann Neurol. 2010 Dec; 68(6): 915-24

Kolodziej A., Schulz S., Guyon, A., Wu D.F., Pfeiffer M., Ödemis V., Hollt V., Stumm R.:Tonic Activation of CXC Chemokine Receptor 4 in Immature Granule Cells Supports Neurogenesis in the Adult Dentate Gyrus. J. Neuroscience. 2008; 28 (17): 4488-4500

Ödemis V., Boosmann K., Dieterlen MT, Engele J.: The chemokine SDF-1 controls multiple steps of myogenesis through atypical PKCzeta.. J. Cell. Sci. 2007; 120(Pt 22): 4050-9

Ödemis V., Lamp E., Pezeshki G., Moepps B., Schilling K., Gierschik P., Littman DR, Engele J.: Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis. Mol. Cell. Neurosci. 2005; 30(4): 494-505

Ödemis V., Moepps B., Gierschik P., Engele J.: Interleukin-6 and cAMP induce stromal cell-derived factor-1 chemotaxis in astroglia by up-regulating CXCR4 cell surface expression. Implications for brain inflammation. J. Biol. Chem. 2002; 277(42): 39801-8

Ruf S., Ödemis V., Thasler W., Babl-Weisbarth M., Rose C.: Therapy of Pyoderma fistulans sinifica, Zbl Chir 1998;123:601

Evers B., Gerngroß H., Ödemis V.: Tourniquet ischaemia and intramuscular oxygen partial pressure during knee arthroscopy. In: Hartel W. (eds) Clinic and research in surgery under the aspect of efficiency and economy. Langenbeck's Archive for Surgeryvol 1997 Springer, Berlin, Heidelberg

Evers B., Ödemis V., Gerngross H.: Intramuscular oxygen partial pressure in patients with chronic exertional compartment syndrome (CECS). Adv. Exp. Med. Biol. 1997; 428: 311-316

Evers B., Ödemis V., Gerngross H.: Oxygen partial pressure in the anterior tibial muscle during and after knee surgery with tourniquet control. Adv. Exp. Med. Biol. 1997; 428: 317-325

Current position

since 2023
Medical Scientist of the UMO
since 2017
Research assistant in the Department of Anatomy in the Department for Human Medicine at the University of Oldenburg

Academic training and scientific career

since 2017
Research assistant in the Department of Anatomy in the Department of Human Medicine at the University of Oldenburg

2010 - 2016
Research assistant at the Institute of Neuroanatomy, Centre for Experimental Medicine, University Medical Center Hamburg-Eppendorf

2004 - 2009
Research assistant at the Institute of Cell and Neurobiology, Centre for Anatomy, Charité - Universitätsmedizin Berlin

PhD topic: "The importance of CALEB/NGC for the differentiation of dendrite trees"
Evaluation: summa cum laude

2003 - 2004
Research assistant in the Department of Cell Biology at the Institute of Zoology, Technische Universität Carolo-Wilhelmina zu Braunschweig

1998 - 2003
Studied Biology at the Technische Universität Carolo-Wilhelmina zu Braunschweig; Diploma thesis in the Department of Cell Biology at the Institute of Zoology, Technische Universität Carolo-Wilhelmina zu Braunschweig

Diploma thesis: "Influence of the phosphorylation of the microfilament protein profilin on its interaction with different ligands"

Memberships in scientific societies

• Neuroscience Society
• German Anatomical Society

Kheyrollah M, Brandt N, Bräuer AU, Schrader S, Mertsch S. The role of lysophosphatidic acid and its receptors in corneal nerve regeneration. Ocul Surf. 2024 Dec 20;36:10-18. doi: 10.1016/j.jtos.2024.12.006. Epub ahead of print. PMID: 39709127.

Gray N, Limberg MM, Wiebe D, Weihrauch T, Langner A, Brandt N, Bräuer AU, Raap U. (2022) Differential Upregulation and Functional Activity of S1PR1 in Human Peripheral Blood Basophils of Atopic Patients. Int. J. Mol. Sci. 2022, 23(24), 16117; https://doi.org/10.3390/ijms232416117 (registering DOI).

Brandt N, Willmer JP,. Ayon-Olivas MS, Banicka V, Witt M, Wree A, Groß I, Gläser A, Hausmann J, Bräuer AU. (2022) PRG3 and PRG5 C-Termini: Important Players in Early Neuronal Differentiation. Int. J. Mol. Sci. 2022, 23, 13007.

Gross I, Brandt N, Vonk D, Köper F, Wöhlbrand L, Rabus R, Witt M, Heep A, Plösch T, Hipp MS, Bräuer AU. (2022) Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination. Front Cell Neurosci. 2022 Apr 15;16:797588. doi: 10.3389/fncel.2022.797588.

Van Bulck M, Brandt N, Claus RA, Graeler M, Braeuer AU (2022). Aβ-Induced Alterations in Membrane Lipids Occur before Synaptic Loss Appears. Int J Mol Sci. 2022 Feb 19;23(4):2300. doi: 10.3390/ijms23042300.

Brandt N, Löffler T, Fester L,Rune GM (2020) Sex-specific features of spine densities in the hippocampus; Sci Rep 2020 Jul 9;10(1):11405. doi: 10.1038/s41598-020-68371

Brandt N, Fester L, Rune GM (2020) Neural sex steroids and hippocampal synaptic plasticity; Vitam Horm 2020 Jul 3 114:125-143. doi: 10.1016/bs.vh.2020.06.001.

Gläser A, Hammerl F, Gräler MH, Coldewey SM, Völkner C, Frech MJ, Yang F, Luo J, Tönnies E, von Bohlen Und Halbach O, Brandt N, Heimes D, Neßlauer AM, Korenke GC, Owczarek-Lipska M, Neidhardt J, Rolfs A, Wree A, Witt M, Bräuer AU. Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism. Int J Mol Sci. 2020 Jun 24;21(12):E4502. doi: 10.3390/ijms21124502.

Brandt N, Vierk R, Fester L, Anstötz M, Zhou L, Heilmann LF, Kind S, Steffen P, Rune GM (2019) Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Neurosteroids; Cereb Cortex 2020 Apr 14;30(4):2627-2641. doi: 10.1093/cercor/bhz265.

Brandt N, Rune GM (2019) Sex-dependency of oestrogen-induced structural synaptic plasticity: Inhibition of aromatase versus application of estradiol in rodents; Eur J Neurosci 2019 Aug 12. doi: 10.1111/ejn.14541.

Meseke M, Pröls F, Schmahl C, Seebo K, Kruse C, Brandt N, Fester L, Zhou L, Bender R, Rune GM (2018) Reelin and aromatase cooperate in ovarian follicle development; Sci Rep 2018 Jun 7;8(1):8722. doi: 10.1038/s41598-018-26928-x.

Bender RA, Zhou L, Vierk R, Brandt N, Keller A, Gee CE, Schäfer MKE, Rune GM (2016) Sex-dependence of aromatase-mediated synaptic plasticity in the basolateral amygdala; J Neurosci, 2017;37(6):1532-1545.

Fester L, Brandt N, Windhorst S, Pröls F, Bläute C, Rune GM (2015) Control of aromatase in hippocampal neurons. J Steroid Biochem Mol Biol. 2015 Oct12. pii: S0960-0760(15)30109-6. doi: 10.1016/j.jsbmb.2015.10.009. [Epub ahead of print] Review.

Koester JD, Leggewie B, Blechner C, Brandt N, Fester L, Rune GM, Schweizer M, Kindler S, Windhorst S (2015) Inositol, 1,4,5- triphosphate-3kinase-A controls morphology of hippocampal dendritic spines. Cell Signal. 2015 Oct 28. pii: S0898-6568(15)00309-5. doi: 10.1016/j.cellsig.2015.10.016. [Epub ahead of print].

Brandt N, Vierk R, Fester L, Zhou L, Imholz P, Rune GM (2014) Gender and the effects of steroid hormones in the central nervous system. Federal Health Gazette Health Research Health Protection. 2014 Sep;57(9):1054-60. doi: 10.1007/s00103-014-2014-4. German.

Vierk R, Brandt N, Rune GM (2014) Hippocampal estradiol synthesis and its significance for hippocampal synaptic stability in male and female animals. Neuroscience. 2014 May 15;274C:24-32. doi: 10.1016/j.neuroscience.2014.05.003. [Epub ahead of print] Review.

Zhou L, Fester L, Haghshenas S, de Vrese X, Hacht RV, Gloger S, Brandt N, Bader M, Vollmer G, Rune GM (2014) Oestradiol-induced synapse formation in the female hippocampus: roles of estrogen receptor subtypes. J Neuroendocrinol. 2014 Apr 30. doi: 10.1111/jne.12162. [Epub ahead of print].

Prange-Kiel J, Schmutterer T, Fester L, Zhou L, Imholz P, Brandt N, Vierk R, Jarry H, Rune GM (2013) Endocrine regulation of estrogen synthesis in the hippocampus? Prog Histochem Cytochem. 2013 Jul 29. doi:pii: S0079-6336(13)00013-2. 10.1016/j.proghi.2013.07.002. [Epub ahead of print].

Brandt N, Vierk R, Rune GM (2013) Sexual dimorphism in estrogen-induced synaptogenesis in the adult hippocampus. Int J Dev Biol. 2013;57(5):351-6. doi: 10.1387/ijdb.120217gr.

Vierk R, Glassmeier G, Zhou L, Brandt N, Fester L, Dudzinski D, Wilkars W, Bender RA, Lewerenz M, Gloger S, Graser L, Schwarz J, Rune GM (2012) Aromatase inhibition abolishes LTP generation in female mice by destabilising the spine cytoskeleton. J Neurosci, 2012.

Wilkars W, Liu Z, Lewis AS, Stoub TR, Ramos EM, Brandt N, Nicholson DA, Chetkovich DM, Bender RA (2012) 1. regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms. PLoS One. 2012;7(2):e32181. Epub 2012 Feb 21.

Brandt N, Franke K, Johannes S, Buck F, Harder S, Hassel B, Nitsch R, and Schumacher S (2008) B56b, a regulatory subunit of protein phosphatase 2A, interacts with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching. FASEB J, 2008 Jul;22(7):2521-33. epub 2008 Apr 2.

Brandt N, Franke K, Rasin MR, Baumgart J, Vogt J, Khrulev S, Hassel B, Pohl EE, Sestan N, Nitsch R, and Schumacher S (2007) The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity. EMBO J 26, 2371-2386.

Current position

Since 2021
Inter-faculty research assistant in anatomical teaching at the University of Oldenburg

Academic education and scientific career

2018-2020
Research assistant at the Institute of Anatomy and Cell Biology, Albert-Ludwigs-University Freiburg Research focus: interneuron development/ epigenetics

2011- 2014
Marie Curie Fellow at the Department of Biomedical Science, Sheffield University, Sheffield, UK, research focus: Inner ear development

2002-2010
PhD student/ research assistant at the Umea Centre for Molecular Medicine, Umea Universitet, Umea, Sweden.

PhD 2009
PhD topic: "Early development of the olfactory placode and early rostrocaudal patterning of the caudal neural tube"

2002
Research assistant in the Department of Developmental Biology at the Institute I of the Biological School of the Albert-Ludwigs-University Freiburg.

1998 - 2002
Studied Biology at the Albert-Ludwigs-University of Freiburg; Diploma thesis in the Department of Developmental Biology at the Institute I of the Faculty of Biology of the Albert-Ludwigs-University of Freiburg

Diploma topic: "Characterisation of the homeobox-encoding gene mnr2 in zebrafish"

1995-1998
Studied biology at the Friedrich Schiller University Jena.

Maier EC, Ödemis V, Bräuer AU. Digitally based clinical-orientated anatomy: the future of teaching. Die Chirurgie. https://doi.org/10.1007/s00104-024-02211-w. 08 January 2025.

Cheffer A, Garcia-Miralles M, Maier E, Akol I, Franz H, Srinivasan VSV, Vogel T. (2023) DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons. Cerebral Cortex, doi: https://doi.org/10.1093/cercor/bhad281.

Baxendale S, Maier EC, Obholzer ND, Burbridge S, Zinski J, Tuazon FB, van Hateren NJ, Garcia Romero MM, Marzo M, Yokoya K, Knight RD, Megason SG, Mullins MC, Whitfield TT. (2023) Bmper is required for morphogenesis of the anterior and posterior semicircular canal ducts in the developing zebrafish inner ear. bioRxiv 2021.06.27.450014; doi: https://doi.org/10.1101/2021.06.27.450014

Maier EC, Whitfield T.: RA and FGF signalling are required in the zebrafish otic vesicle to pattern and maintain ventral otic identities, PLoS Genetics 2014 Dec 4;10(12).

Maier EC, Saxena A, Alsina B, Bronner ME, Whitfield T: Sensational placodes: Neurogenesis in the otic and olfactory system, Dev Biol. 2014 May 1;389(1).

Maier E, Nord H, von Hofsten J, Gunhaga L.: A balance of BMP and Notch activity regulates neurogenesis and olfactory nerve formation, PLoS ONE, 2011 Feb 23;6(2).

Maier E, von Hofsten J, Nord H, Fernandes M, Paek H, Hébert JM, Gunhaga L.: Opposing activities of FGF and BMP specify respiratory versus sensory olfactory epithelial cell fate decisions, Development. 2010 May;137 (10). (recommended by F1000).

Maier E, Gunhaga L: Dynamic expression of neurogenic markers in the developing chick olfactory epithelium, Dev Dyn. 2009, Jun;238(6).

Nordström U, Maier E, Jessell TM, Edlund T: An early role for Wnt signalling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity, PLoS Biol. 2006, Jul 18;4(8).

Wendik B, Maier E, Meyer D: Zebrafish mnx genes in endocrine and exocrine pancreas formation, Dev Biol. 2004, Apr 15;268(2).

Current position

Since 2022
Research assistant in the Department of Anatomy in the Department of Human Medicine at the University of Oldenburg

Academic training and scientific career

2017-2020
Marie Skłodowska-Curie Actions scholarship holder at the European Molecular Biology Laboratory in Heidelberg and Grenoble, and at the Department of Nuclear Medicine at Münster University Hospital

2014-2016
EMBO Long-Term Scholarship holder in the Department of Vascular Cell Biology at the Max Planck Institute for Molecular Biomedicine in Münster

2013-2014
Research Associate in the Department of Vascular Cell Biology at the Max Planck Institute for Molecular Biomedicine in Münster

2008-2013
Research assistant (PhD student) in the Department of Biochemistry at the Netherlands Cancer Research Institute in Amsterdam
PhD topic: "Structural and biochemical characterisation of autotaxin"

2002-2008
Studied biology at the Westfälische Wilhelms University of Münster, University of Michigan (USA) and at the University of Utrecht (Netherlands)
Topic of the Diplom thesis: "Characterisation of Hsp90 by segmental isotope labelling"

1. Chen Y, Hausmann J, Zimmermann B, Helgers SOA, Dömer P, Woitzik J, Raap U, Gray N, Büttner A, Koch KW, Bräuer AU. Retinal degeneration protein 3 mutants are associated with cell-cycle arrest and apoptosis. Cell Death Discovery 11 (1):175, 2025

2. Becker L, Hausmann J, Wellpott R, Hartmann AM. Highly conserved ion binding sites are not all functionally relevant in mouse KCC4. Frontiers in Molecular Biosciences 12:1556250, 2025

3. Brandt N*, Köper F*, Hausmann J, Bräuer AU. Spotlight on plasticity-related genes: Current insights in health and disease. Pharmacology & Therapeutics 260:108687, 2024

4. Eymery MC, Boumendjel A, McCarthy ^AA§, Hausmann^J§ Linking the Autotaxin-LPA Axis to Medicinal Cannabis and the Endocannabinoid System. International Journal of Molecular Sciences 25 (6):3212, 2024

5. Eymery MC, Nguyen K, Basu S, Hausmann J, Nguyen VT, Seidel HS, Gutierrez L, Boumendjel A, McCarthy AA. Discovery of potent chromone-based autotaxin inhibitors inspired by cannabinoids. European Journal of Medicinal Chemistry 263:115944, 2023

6. Becker L, Hausmann J, Hartmann AM. Both chloride binding sites are required for KCC2 mediated-transport. Journal of Biological Chemistry 299(10):105190, 2023

7. Eymery MC, McCarthy ^AA§, Hausmann^J§. Linking medicinal cannabis to autotaxin-lysophosphatidic acid signalling. Life Science Alliance 9;6(2):e202201595, 2023

8. Brandt N, Willmer JP, Ayon-Olivas MS, Banicka V, Witt M, Wree A, Groß I, Gläser A, Hausmann J, Bräuer AU. PRG3 and PRG5 C-Termini: Important Players in Early Neuronal Differentiation. International Journal of Molecular Science 23(21):13007, 2022

9. Hausmann^J§, Joosten R, van Zeijl L, Hipgrave Ederveen AL, Moolenaar WH, Perrakis ^A§. Structural Snapshots of Autotaxin/ENPP2 and their implications for the catalysis. Journal of Structural Biology 195(2):199-206, 2016.

10. Keune WJ, Hausmann J*, Bolier R*, Tolenaars D, Kremer A, Heidebrecht T, Joosten R, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink ^R§, Perrakis ^A§. Steroid binding to autotaxin links bile salts and lysophosphatidic acid signalling. Nature Communication 7:11248, 2016.

11. Houben AJ, van Wijk XM, van Meeteren LA, van Zeijl L, van de Westerlo EM, Hausmann J, Fish A, Perrakis A, van Kuppevelt TH, and Moolenaar WH. The Polybasic Insertion in Autotaxin alpha Confers Specific Binding to Heparin and Cell Surface Heparan Sulfate Proteoglycans. Journal of Biological Chemistry 288(1): 510-519, 2013.

12. Hausmann J, Perrakis A, and Moolenaar WH. Structure-function relationships of autotaxin, a secreted lysophospholipase D. Advances in Biological Regulation 53(1): 112-117, 2013.

13. Kryshtafovych A, Moult J, Bartual SG, Bazan JF, Berman H, Casteel DE, Christodoulou E, Everett JK, Hausmann J, Heidebrecht T, Hills T, Hui R, Hunt JF, Seetharaman J, Joachimiak A, Kennedy MA, Kim C, Lingel A, Michalska K, Montelione GT, Otero JM, Perrakis A, Pizarro JC, van Raaij MJ, Ramelot TA, Rousseau F, Tong L, Wernimont AK, Young J, and Schwede T. Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins79 Suppl 10: 6-20, 2011.

14. Albers HMHG, Hendrickx LJ, van Tol RJ, Hausmann J, Perrakis A, and Ovaa H. Structure-based design of novel boronic acid-based inhibitors of autotaxin. Journal of Medicinal Chemistry 54(13): 4619-4626, 2011.

15. Hausmann J*, Kamtekar S*, Christodoulou E, Day JE, Wu T, Fulkerson Z, Albers HMHG, van Meeteren LA, Houben AJ, van Zeijl L, Jansen S, Andries M, Hall T, Pegg LE, Benson TE, Kasiem M, Harlos K, Kooi CW, Smyth SS, Ovaa H, Bollen M, Morris ^AJ§, Moolenaar ^WH§, and Perrakis ^A§. Structural basis of substrate discrimination and integrin binding by autotaxin. Nature Structural & Molecular Biology 18: 198-204, 2011.

16. Karagoz GE, Duarte AM, Ippel H, Uetrecht C, Sinnige T, van Rosmalen M, Hausmann J, Heck AJ, Boelens R, and Rudiger SG. N-terminal domain of human Hsp90 triggers binding to the cochaperone p23. Proceedings of the National Academy of Sciences of the United States of America 108(2): 580-585, 2011.

17. Hausmann J*, Christodoulou E*, Kasiem M, De Marco V, van Meeteren LA, Moolenaar WH, Axford D, Owen RL, Evans G, and Perrakis A. Mammalian cell expression, purification, crystallisation and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein. Acta Crystallographica Section F 66(Pt 9): 1130-1135, 2010.

18. Day JE, Hall T, Pegg LE, Benson TE, Hausmann J, and Kamtekar S. Crystallisation and preliminary X-ray diffraction analysis of rat autotaxin. Acta Crystallographica Section F 66(Pt 9): 1127-1129, 2010.

19. Cremers CM, Reichmann D, Hausmann J, Ilbert M, and Jakob U. Unfolding of metastable linker region is at the core of Hsp33 activation as a redox-regulated chaperone. The Journal of Biological Chemistry 285(15): 11243-11251, 2010.

* These authors contributed equally to the work

§ Shared corresponding authors

Current position

Since 2025
Research assistant at the Department of Anatomy in the Department of Human Medicine at the University of Oldenburg

Academic training and scientific career

2022-2024
Research Associate at the Department Institute of Anatomy and Vascular Biology University of Münster- Germany

2022
Publication of online courses as an honorary lecturer on the Faradars platform.

2019-2022
PhD at Jülich research centre INM-10- Germany

PhD topic: Structural analysis of the synaptic organisation of layer 1 of the neocortex of the human temporal lobe using high-resolution electron microscopy and quantitative synaptic 3D models

2017-2019
Research Associate at the Department of Institute of Anatomy, Birjand Medicine University- Iran

2016
6 months research stay at the Epilepsy Research Centre, Münster, Germany

2013-2016
Doctorate at Isfahan University of Medicine- Iran

PhD topic: Investigation of the effects of maternal diabetes on neurogenesis in the developing hippocampus of rat neonates.

Memberships in scientific societies

German Anatomical Society

Iranian Anatomical Society

Rollenhagen Astrid, Sadeghi Dastjerdi Akram, Walkenfort Bernd, Hilgetag Claus C, Sätzler Kurt, Lübke Joachim HR (2024) Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex eLife 13:RP99473. https://doi.org/10.7554/eLife.99473.1

2021

Neurotrophic Factors in Alzheimer's disease: Pathogenesis and Therapy. Lübke J, Idoon F, Mohasel-roodi M, Alipour F, Hami J, Ehteshampour A, Mostafaee H, Sadeghi A. Acta Neurobiologie Experimentalis Journal.2021.

Neuroprotective effects of vitamin C and garlic on glycoconjugates changes of cerebellar cortex in lead-exposed rat offspring. Sadeghi A, Khordad E, Ebrahimi V, Raoofi A, Alipour F, Ebrahimzadeh-Bideskan A. J Chem Neuroanat. 2021 Jul;114: 101948.doi: 10.1016/j. jchemneu. 2021.101948. Epub 2021 Mar 27. PMID: 33785394.

2019

Volumetric investigation of the hippocampus in rat offspring due to diabetes in pregnancy-A stereological study. Sadeghi A, Asghari H, Hami J, Mohasel Roodi M, Mostafaee H, Karimipour M, Namavar M, Idoon F. J Chem Neuroanat. 2019 Nov;101: 101669.doi: 10.1016/j. jchemneu.2019.101669. Epub 2019 Aug 20.

A Morphometric Study of Pterion and its Clinical Significance for Brain Surgery. Mohammadi S, Absalan F, Fazel A, Ebrahimi B, Abbasi M, Joghataei MT, Sadeghi A, Sadra Medical Journal 7 (3), 237-242.

2018

The effects of maternal diabetes and insulin treatment on neurogenesis in the developing hippocampus of male rats. Sadeghi A, Esfandiary E, Hami J, Khanahmad H, Hejazi Z, Mardani M, Razavi S. J Chem Neuroanat. 2018 Sep; 91:27-34.doi: 10.1016/j.jchemneu.2018.03.005. Epub 2018 Mar 22. PMID: 29578075.

Neurotrophic Factors and Neurodegenerative Diseases. Mohasel-roodi M, Idoon F, Asghari H, Hami J, Hassanzadehtaheri M, Hosseini M, Sadeghi A. Theranostics Brain Disord 2(5): Tbd.ms.id.555598 (2018).

Morphometric Study of Greater Palatine Canal and Its Significance in block of Maxillary Nerve. Mohammadi S, Ebrahimi B, Kazemian M, Absalan F, Nikravesh MR, Beyhagh 23 (2), 7-12.

P75: Expression of GDNF Genes in the Cerebellum of Rat Neonate Born to Mother with Diabetes. Mohasel Roodi M, Idoon F, Asghari H, Ivar G, Sedeghi A, Hami J, The Neuroscience Journal of Shetaye Khatam 6 (2), 106-106.

2017

Variation of the cephalic and basilic veins: A case report. Sadeghi A, Setayesh Mehr M, Esfandiari E, Mohammadi S, Baharmian H. J Cardiovasc Thorac Res. 2017;9(4): 232-234.doi: 10.15171/jcvtr.2017.40. Epub 2017 Oct 15.

Synaptogenesis in the Cerebellum of Offspring Born to Diabetic Mothers. Hami J, Vafaei-Nezhad S, Sadeghi A, Ghaemi K, Taheri MH, Fereidouni M, Ivar G, Hos seini M. J Pediatr Neurosci. 2017 Jul-Sep; 12(3): 215-221.doi: 10.4103/jpn.-JPN_144_16.

Anti-Inflammatory Effect of Crocus sativus on Serum Cytokine Levels in Subjects with Metabolic Syndrome: A Randomised, Double-Blind, Placebo- Controlled Trial. Kermani T, Zebarjadi M, Mehrad-Majd H, Mirhafez SR, Shemshian M, Ghasemi F, Mohammadzadeh E, Mousavi SH, Norouzy A, Moghiman T, Sadeghi A, Ferns G, Avan A, Mahdipour E, Ghayour-Mobarhan M. Curr Clin Pharma-col. 2017; 12(2):122-126. doi:10.2174/1574884712666170622082737. PMID: 28637418

Effect of Probiotic Soy Milk on Serum Levels of Adiponectin, Inflammatory Me-diators, Lipid Profile, and Fasting Blood Glucose Among Patients with Type II Diabetes Mellitus. Feizollahzadeh S, Ghiasvand R, Rezaei A, Khanahmad H, Sadeghi A, Hariri M. Probiotics Antimicrob Proteins. 2017 Mar; 9(1): 4147.doi:10.1007/s12602-016-9233-y. PMID: 27757829 Clinical Trials.

Beneficial effects of garlic on learning and memory deficits and brain tissue damages induced by lead exposure during juvenile rat growth is comparable to the effect of ascorbic acid. Ghasemi S, Hosseini M, Feizpour A, Alipour F, Sadeghi A, Vafaee F, Mohammadpour T, Soukhtanloo M, Ebrahimzadeh Bideskan A, Beheshti F. Drug Chem Toxicol. 2017 Apr; 40(2): 206-214.doi:10.1080/01480545.2016.1197238. Epub 2016 Jul 7. PMID: 27387089.

2016

A double-blind, randomised and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghay-our-Mobarhan M, Ferns GA. J Complement Integr Med. 2016 Jun 1;13(2): 195-9.doi: 10.1515/jcim-2015-0043.

The Effect of Diabetes Mellitus on Apoptosis in Hippocampus: Cellular and Molecular Aspects. Sadeghi A, Hami J, Razavi S, Esfandiary E, Hejazi Z. Int J Prev Med. 2016 Mar 10;7: 57.doi: 10.4103/2008-7802. 178531.e Collection 2016. PMID: 27076895.

Effect of maternal diabetes on gliogensis in neonatal rat hippocampus. Sadeghi A, Esfandiary E, Hami J, Khanahmad H, Hejazi Z, Razavi S. Adv Biomed Res. 2016 Aug 30;5: 142.doi: 10.4103/2277-9175.187376. e Collection 2016.

Stereological study of the effects of maternal diabetes on cerebellar cortex development in rat. Hami J, Vafaei-Nezhad S, Ghaemi K, Sadeghi A, Ivar G, Shojae F, Hosseini M. Metab Brain Dis. 2016 Jun;31(3):643-52. doi: 10.1007 /s11011-016-9802-5. Epub 2016 Feb 3. PMID: 26842601.

Beneficial effects of L-arginine on 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyri-dine-induced neuronal degeneration in substantia nigra of Balb/c mice. Hami J, Hosseini M, Nezhad SV, Shahi S, Lotfi N, Ehsani H, Sadeghi A. Adv Biomed Res. 2016 Aug 30;5: 140.doi: 10.4103/2277-9175.187374. eCollection 2016.

Protective effects of ascorbic acid and garlic extract against lead induced apoptosis in developing rat hippocampus. Ebrahimzadeh-Bideskan AR, Hami J, Alipour F, Haghir H, Fazel AR, Sadeghi A. Metab Brain Dis. 2016 Oct;31(5): 1123-32.doi: 10.1007/s11011-016-9837-7. Epub 2016 Jun 17.

Altered expression and localisation of synaptophysin in developing cerebellar cortex of neonatal rats due to maternal diabetes mellitus. Hami J, Va-faei-Nezhad 9th S, Ivar G, Sadeghi A, Ghaemi K, Mostafavizadeh M, Hosseini M. Metab Brain Dis. 2016 Dec;31(6): 1369-1380.doi: 10.1007/s11011-016-9864-4.Epub 2016 Jul 7. PMID: 27389246.

The impacts of diabetes in pregnancy on hippocampal synaptogenesis in rat neonates. Vafaei-Nezhad S, Hami J, Sadeghi A, Ghaemi K, Hosseini M, Abedini MR, Haghir H. Neuroscience. 2016 Mar 24;318: 122-33.doi: 10.1016/j.neurosci-ence.2016.01.025. Epub 2016 Jan 18. PMID: 26794272.

Study of Ameliorative Role of Garlic and Ascorbic Acid Consumption On Lead-induced Glycoconjugates Changes in Rat Offspring Hippocampus. Ebra-himzadeh Bideskan A, Sadeghi A, Alipour F, Nikravesh M, Amini S, Sefidgar Teh-rani M, Naseri Gh. Int J Cur Life Sci. 2014 July; 4(7):33983403.

2015

The effects of Ascorbic Acid and Garlic on Bone Mineralisation in Lead Exposed pregnant Rats. Ebrahimzadeh-Bideskan A, Sadeghi A, Alipour F, Kianmehr M. Zahedan Journal of Research in Medical Sciences 2015.

2014

Saffron in metabolic syndrome: its effects on antibody titers to heat-shock proteins 27, 60, 65 and 70. Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Ghayour-Mobarhan M, Ferns GA. J Complement Integr Med. 2014 Feb 6;11(1): 43-9.doi: 10.1515/jcim-2013-0047. PMID:24501162

The Protective Effect of Ascorbic Acid and Garlic Supplementation Against Neu-rogenesis Inhibition Caused by Developmental Lead Exposure In The Dentate Gyrus Of Rat. Alipour F, Ebrahimzadeh Bideskan A, Sadeghi A, Fazel A, Haghir H, Hami J. Compar Clin Pathol. 2014 November; 23(6): 1681-1687. doi: 10.1007/s00580-014-1895-9.

2013

The Effect of Ascorbic Acid and Garlic Administration on Lead-Induced Neural Damage in Rat Offspring's Hippocampus. Sadeghi A, Ebrahimzadeh Bideskan A, Alipour F, Fazel A, Haghir H. Iran J Basic Med Sci. 2013 Feb;16(2):157-64. PMID:24298384